Can you reuse the same palace for different information?

Yes — a palace is reusable, but let the previous content fade first (or rotate palaces) to avoid interference.

Loci are permanent; the images on them are temporary. Once you no longer need last week's list, the images naturally weaken and the loci are free to hold something new. Practical approaches:

• Rotate a handful of "scratch" palaces for temporary lists.
• Wait for old content to decay before overwriting a palace.
• Dedicate certain palaces to permanent knowledge you deliberately keep reviewing.